Guideline of guidelines: a critical appraisal of the evidence for PSA retesting intervals.

ABSTRACT:

Objectives

To summarise the recommendations for prostate-specific antigen (PSA) retesting intervals and to evaluate the evidence cited by each guideline by conducting a systematic review of clinical practice guidelines.

Methods

We searched PubMed and the Turning Research into Practice (TRIP) database for guidelines written in English and developed or updated in 2013-2024. Guideline quality assessment was performed using the AGREE II tool. We narratively synthesised results.

Results

Eleven guidelines were included. Ten (91%) recommended PSA retesting intervals of approximately 2 to 4 years. A total of 37 studies were referenced as evidence for the recommended intervals across the 11 guidelines. Five of these studies (14%) had the objective of determining PSA retesting

SUBMITTER: Collins KK 

PROVIDER: S-EPMC12343985 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature