Magnetic resonance imaging-guided transurethral ultrasound ablation for benign prostatic obstruction: 1-year clinical outcomes of a phase II study.

ABSTRACT:

Objectives

To evaluate the safety and efficacy of magnetic resonance imaging (MRI)-guided transurethral ultrasound ablation (TULSA) as a minimally invasive alternative for benign prostatic obstruction (BPO).

Patients and methods

This prospective, single-centre, early phase II study (NCT03350529) included 30 men with BPO scheduled for primary transurethral resection of the prostate. Assessments over 12 months included uroflowmetry, prostate-specific antigen (PSA) levels, and validated questionnaires at baseline and 3-month intervals. MRI was performed at baseline and at 3 and 12 months. Medication use and adverse events (AEs) were recorded and graded using the Clavien-Dindo classification.

Results

The median patient age at treatment was 67 years. During the 12-month po

SUBMITTER: Viitala A 

PROVIDER: S-EPMC12343988 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature