Genomic and phenotypic characterization of six multidrug-resistant Acinetobacter pittii isolates.

ABSTRACT: The Acinetobacter calcoaceticus-baumannii complex is a significant cause of nosocomial infections. While A. baumannii is the most common and clinically significant member globally, recent studies suggest that A. pittii is an emerging pathogen within the complex. Clinical A. pittii isolates have not been well characterized. In this study, we investigated the genomic and phenotypic characteristics of six clinical A. pittii isolates from five healthcare facilities. All isolates were resistant to ceftazidime and ertapenem, and one was resistant to imipenem and meropenem. Using whole genome sequencing and phylogenetic analysis, we found that isolates were not linked genetically, harbored OXA-type β-lactamase genes, and exhibited a wide array of virulence factors. Plasmids were identified in two

SUBMITTER: Rakovitsky N 

PROVIDER: S-EPMC12344141 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature