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Histopathology of nasopharyngeal and palatine tonsils in Japanese black calves naturally infected with Mycoplasma bovis.


ABSTRACT: Mycoplasma bovis (M. bovis) is an important bacterium in the bovine respiratory disease complex (BRDC), which causes significant economic losses. The nasopharyngeal and palatine tonsils are mucosal-associated lymphoid tissue components that are the initial barrier to respiratory pathogens. In the present study, we investigated 5 pneumonic Japanese black and 3 control calves (2 Japanese black and 1 Holstein). The localization of M. bovis in the nasopharyngeal, palatine tonsils, and lungs was examined using nested and multiplex polymerase chain reaction (PCR), histopathology, and in situ hybridization (ISH) techniques. Nested PCR revealed that all examined tissues from all pneumonic calves were positive for M. bovis infection, but not the control. Histopathology revealed suppurative nasophar

SUBMITTER: Ahmed AE 

PROVIDER: S-EPMC12344299 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature