Construction of a register-based severity index for anorexia nervosa in Denmark: Association with overall and cause-specific mortality.

ABSTRACT:

Background

Considering the high likelihood of chronicity, it is imperative to understand the risk factors and outcomes associated with severe anorexia nervosa (AN), for which Danish registers provide a unique opportunity. We developed a measure of AN severity adapted from clinical literature for use in register-based research.

Methods

The study population included all Danish individuals born between 1963 and 2007 who were diagnosed with AN from 1969 to 2013. Using register data, we constructed the anorexia nervosa register-based severity index (AN-RSI), incorporating early or late illness onset, number of inpatient admissions and outpatient treatments, cumulative treatment length, and illness duration, each weighted based on clinical importance. Associations between AN-RSI s

SUBMITTER: Larsen JT 

PROVIDER: S-EPMC12344468 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature