Clinicopathologic Associations in a Large International Cohort of Patients With Giant Cell Arteritis.

ABSTRACT:

Objective

In addition to aiding in diagnosis, histopathologic findings from temporal artery biopsy (TAB) specimens in giant cell arteritis (GCA) may be valuable for their associations with clinical features of the disease. This study was undertaken to compare histopathologic findings on TAB with biopsy interpretation and demographic, clinical, and imaging features at time of diagnosis.

Methods

Patients with a clinical diagnosis of GCA who had a TAB were selected from an international, multicenter observational cohort of vasculitis. Associations between demographic, clinical, radiographic, and histopathologic features were identified using bivariate testing and multivariate regression modeling.

Results

Of 705 patients with GCA who underwent TAB, 69% had histopathologic

SUBMITTER: Putman MS 

PROVIDER: S-EPMC12344520 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature