Impact of Daytime and Nighttime Blood Pressure and Nocturnal Blood Pressure Fall on Heart Failure Risk in Treated Hypertension.

ABSTRACT:

Background

To evaluate the impact of daytime, nighttime, and nocturnal blood pressures (BPs) fall on heart failure (HF).

Methods

We analyzed data from five cohorts including 15,526 treated hypertensive patients, experiencing 625 HF events, by study-level meta-analysis. The pooled hazard ratios (HRs) and 95% confidence intervals (CIs) for 1SD increase in BP parameters or per group were calculated.

Results

When individually analyzed after adjustment for covariates, clinic systolic BP (SBP) (HR 1.20, 95% CI 1.01-1.43), daytime SBP (HR 1.34, 95% CI 1.06-1.70), nighttime SBP (HR 1.43, 95% CI 1.20-1.71), nighttime diastolic BP (DBP) (HR 1.26, 95% CI 1.05-1.52), % of nocturnal SBP fall (HR 0.81, 95% CI 0.75-0.88), and nondipping (HR 1.64, 95% CI 1.54-1.98) were associated wi

SUBMITTER: Coccina F 

PROVIDER: S-EPMC12344654 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature