Genomic epidemiology and antimicrobial resistance of <i>Corynebacterium macclintockiae</i>, the predominant species of human pathogens within the <i>Corynebacterium jeikeium</i> complex.

ABSTRACT: Genomic characteristics and optimal treatment of Corynebacterium jeikeium remain largely unknown. We collected clinical information and performed whole-genome sequencing analysis of the causative strains of six cases of C. jeikeium infection at a single hospital over a 9-year period. Additionally, whole-genome sequencing analysis was performed on 33 C. jeikeium strains from cases of bloodstream infection at eight hospitals. Antimicrobial susceptibility testing was performed, and the results were compared to the resistance genes identified. Publicly available genome data of strains of C. jeikeium complex, consisting of C. jeikeium sensu stricto, Corynebacterium macclintockiae, and Corynebacterium evansiae, worldwide, were combined with

SUBMITTER: Harada S 

PROVIDER: S-EPMC12345161 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature