Long-term prognostic value of native myocardial tissue relaxation parameters (T1, T2, and T1ρ) in patients with precapillary pulmonary hypertension.

ABSTRACT: Quantitative native cardiovascular magnetic resonance imaging (CMR) techniques such as T1, T2, and T1ρ mapping can provide myocardial tissue characteristics non-invasively. The objective of this study was to evaluate the alterations of T1, T2, and T1ρ in patients with precapillary pulmonary hypertension (PH) and their prognostic value. We prospectively enrolled 35 PH patients and 15 healthy controls between 2014 and 2017. PH patients were followed for all-cause death. CMR functional and tissue relaxation parameters were acquired and analyzed. Multivariate Cox regression models and time-dependent receiver operator characteristic (ROC) curves were constructed to determine the risk assessment/predictive value of T1, T2, and T1ρ for all-cause mortality. During a median follow-up of 79 months (

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12346376 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature