A Multicenter Pilot Randomized Trial of a Lifestyle Intervention to Prevent Type 2 Diabetes in High-Risk Individuals.

ABSTRACT:

Background

Type 2 diabetes (T2D) is a growing public health concern, particularly in low- and middle-income countries. Although prediabetes is a major risk factor for T2D, it remains largely underdiagnosed and untreated. Structured lifestyle interventions have proven effective in preventing diabetes, but their feasibility within the Brazilian public health system remains unclear.

Methods

This multicenter pilot randomized controlled trial assessed the feasibility of a culturally adapted lifestyle intervention (PROVEN-DIA) across the five regions of Brazil. A total of 220 adults at high risk for T2D were randomized to an intervention group or a control group (usual care) and followed for three months. Both groups received similar educational content on healthy eating and physi

SUBMITTER: Pagano R 

PROVIDER: S-EPMC12348132 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature