Kidney Transplant Outcomes in Recurrent Versus <i>De Novo</i> IgA Nephropathy.

ABSTRACT:

Introduction

IgA nephropathy (IgAN) recurs frequently in kidney transplants, although the reported frequency of recurrence varies because many studies do not distinguish recurrent IgAN from IgAN occurring de novo in the allograft. In addition, there are only limited studies of graft outcomes in patients with recurrent IgAN.

Methods

We retrospectively examined 264 kidney transplant biopsies with glomerular IgA deposits, distinguishing whenever possible recurrent versus de novo IgAN, and compared clinical and pathologic features of biopsies of patients within these groups. We also examined graft outcomes in patients with available follow-up to identify findings associated with graft survival.

Results

A significantly greater fraction of biopsies with recurr

SUBMITTER: Haas M 

PROVIDER: S-EPMC12348186 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature