The Translational Research Program in Cancer Differences across Populations.

ABSTRACT:

Background

Cancer incidence and mortality vary substantially across populations. The Translational Research Program in Cancer Differences across Populations (TRPCDP) was established in 2020 to address differences in cancer incidence and mortality rates within the United States, with a particular focus on colorectal cancer.

Methods

The TRPCDP centralized data acquisition and harmonization across three sites in the United States to create a well-annotated resource of colorectal cancer tumors across four populations: African American/Black, Alaska Native, Hispanic/Latino/Latina, and non-Hispanic White. Using a case-control framework, patients with lethal colorectal cancer were matched to two controls with nonlethal colorectal cancer. Formalin-fixed, paraffin-embedded tumor and

SUBMITTER: Figueiredo JC 

PROVIDER: S-EPMC12349377 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature