Global longitudinal strain as a predictor of outcomes in chronic Chagas´ cardiomyopathy.

ABSTRACT:

Introduction

Chronic Chagas cardiomyopathy (CCC) is associated with a high incidence of cardiovascular events. Global longitudinal strain (GLS) is useful in predicting adverse cardiovascular outcomes in several cardiomyopathies. However, its prognostic value in CCC is not well established.

Methods

This study was a retrospective echocardiography analysis with prospective follow-up of CCC subjects. GLS was defined as the average of three apical peak longitudinal strain measurements of the LV using vendor-independent software. GLS groups were defined according to tertiles: (1) GLS ≤ -18.4%, (2) GLS > -18.4% and <-13.8%, and (3) GLS ≥ -13.8%. The primary outcome was a composite of death, hospitalization, sustained ventricular tachycardia (SVT), new heart failure, any systemic em

SUBMITTER: Romano MMD 

PROVIDER: S-EPMC12349712 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature