Histopathologically confirmed radiation necrosis: Risk factors and clinical outcomes in patients with primary brain tumors.

ABSTRACT:

Background

Radiation necrosis is a recognized complication following radiotherapy for primary brain tumors, presenting diagnostic and therapeutic challenges, and potentially masquerading as tumor recurrence. This study aims to delineate the clinical trajectory, management strategies, and outcomes of histologically confirmed radiation necrosis in patients treated for primary brain tumors.

Methods

We conducted a retrospective review of patients who underwent surgical intervention for suspected tumor recurrence at our institution between 2010 and 2022, following adjuvant radiotherapy. Cases with histopathologically confirmed radiation necrosis were identified and analyzed for onset, clinical symptoms, radiological features, correlation with radio- and chemotherapy, management a

SUBMITTER: Hazaymeh M 

PROVIDER: S-EPMC12349754 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature