Human Papillomavirus Persistence, Recurrence, and Incidence in Early Childhood.

ABSTRACT:

Background

Little is known on the vertical transmission of human papillomavirus (HPV) and on the dynamics of HPV among children. Our objective was to determine the risk of HPV recurrence, persistence, and incidence over 2 years of age among children born to HPV-positive mothers.

Methods

We conducted the HERITAGE study among pregnant women recruited between 2010 and 2016 in Canada. HPV DNA testing was done on vaginal samples collected during the first and third trimesters of pregnancy, and on conjunctival, oral, pharyngeal, and genital samples collected in children from birth and at every 3-6 months up to 2 years. We estimated the probability of HPV vertical transmission, and of HPV recurrence, persistence, and incidence among children during follow-up. Time to clear HPV amon

SUBMITTER: Benard EA 

PROVIDER: S-EPMC12349960 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature