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ABSTRACT: Background
Hand osteoarthritis (HOA), a disabling musculoskeletal disorder, poses a significant global burden but remains understudied relative to other osteoarthritis (OA) subtypes. Using data from the Global Burden of Disease (GBD) Study 1990-2021, this analysis characterizes HOA epidemiology, temporal trends, and future projections.Methods
GBD 2021 data on HOA incidence, prevalence, and disability-adjusted life-years (DALYs) were stratified by sex, age, Socio-demographic Index (SDI) regions, GBD regions, and countries. Temporal trends (1990-2021) were assessed via estimated annual percentage changes (EAPCs), with future projections (2022-2046) generated using an age-period-cohort (APC) model.Results
In 2021, HOA accounted for 10.37 million incidence cases, 194.28
SUBMITTER: Wei J
PROVIDER: S-EPMC12350485 | biostudies-literature | 2025
REPOSITORIES: biostudies-literature