Ten-year follow-up of degenerative spinal lesions on radiographs and MRI in axial spondyloarthritis: results of the DESIR (DEvenir des spondylarthropathies indifferenciees recentes) cohort.

ABSTRACT:

Objectives

To investigate the occurrence of spinal degenerative lesions (DL)s in axial spondyloarthritis (axSpA) inception cohort in radiographs and MRI over 10 years (10Y), to assess their changes over time and factors associated with them.

Methods

Whole spine MRI and cervical and lumbar spine radiographs at baseline/5Y/10Y of patients with axSpA from the DESIR cohort were assessed for DLs by three readers. For descriptive analyses, DLs were defined by agreement between ≥ 2/3 readers or using the average of their assessments, at the patient level (≥ 1 lesion/patient). To assess the progression of DLs over time, we used multilevel generalised estimating equation models considering individual reader data.

Results

Imaging was available for 330 patients (mean age 34 [9]

SUBMITTER: Pina Vegas L 

PROVIDER: S-EPMC12350588 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature