Spectral and network investigation reveals distinct power and connectivity patterns between phasic and tonic REM sleep.

ABSTRACT: Although rapid eye movement (REM) sleep is often thought of as a singular state, it consists of two substates, phasic and tonic REM, defined by the presence (respectively absence) of bursts of rapid eye movements. These two substates have distinct EEG signatures and functional properties. However, whether they exhibit regional specificities remains unknown. Using intracranial EEG recordings from 31 patients, we analyzed expert-labeled segments from tonic and phasic REM and contrasted them with wakefulness segments. We assessed the spectral and connectivity content of these segments using Welch's method to estimate power spectral density and the phase locking value to assess functional connectivity. Overall, we found a widespread power gradient between low and high frequencies (p < 0.05, Co

SUBMITTER: Avigdor T 

PROVIDER: S-EPMC12351276 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature