EBV-positive inflammatory follicular dendritic cell sarcoma occurring in different organs: a case report and literature review.

ABSTRACT:

Background

Epstein-Barr virus (EBV)-positive inflammatory follicular dendritic cell sarcoma (EBV+ IFDCS) represents a low-grade malignancy arising from the proliferation of follicular dendritic cells. This distinct and rare subtype, characterized by abundant lymphoplasmacytic infiltration, is closely linked to EBV infection and is seldom encountered in clinical practice.

Methods

Presented here are three cases of primary EBV+ IFDCS, occurring in the liver and spleen. This study systematically analyzed the clinical presentations, radiological features, and pathological characteristics of our cases. Additionally, we conducted a comprehensive review of the respective characteristics documented in the existing literature.

Results

We present three cases of EBV+ IFDCS, with

SUBMITTER: Bai W 

PROVIDER: S-EPMC12351499 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature