Construction and validation of a nomogram to identify risk of sleep disorders in gastrointestinal tumor patients undergoing chemotherapy.

ABSTRACT:

Objectives

This study aimed to identify risk factors for sleep disorders in gastrointestinal cancer patients undergoing chemotherapy and to construct a predictive nomogram model, validated both internally and externally.

Methods

A prospective study was conducted (ChiCTR2400085854), involving 308 patients from Jiangnan University Affiliated Central Hospital (Oct 2023-Aug 2024) for model development. Sleep quality and symptom burden were assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Memorial Symptom Assessment Scale-Chinese version (MSAS-Ch). Independent risk factors were identified by multivariate logistic regression. A nomogram was constructed using R software and validated internally with 1000 bootstrap resamples and externally with 103 patients (Aug-Dec

SUBMITTER: Cao Q 

PROVIDER: S-EPMC12351578 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature