Extratumoral signs on mammography as a novel prognostic indicator for breast cancer: evidence from malignant nonspiculate and noncalcified masses.

ABSTRACT:

Objectives

To evaluate the prognostic significance of extratumoral structural abnormalities associated with malignant nonspiculate and noncalcified masses (NSNCMs) detected on mammography.

Methods

Data from 354 breast cancer patients with mammographically detected NSNCMs between December 2017 and December 2018 were retrospectively analyzed. Cox regression analysis was performed to assess the impact of mammographic findings, particularly extratumoral structural abnormalities such as parenchymal and trabecular signs, on progression-free survival (PFS). Additionally, Kaplan-Meier survival curves were used for risk stratification.

Results

The median follow-up period was 74 months (range: 10-83 months). Disease progression occurred in 122 patients (34.5%). Cox regression a

SUBMITTER: Xu Y 

PROVIDER: S-EPMC12351602 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature