Transcriptomic-proteomic analysis reveals the regulatory mechanisms of Alfalfa (<i>Medicago sativa</i>) in response to <i>Fusarium acuminatum</i>.

ABSTRACT: Alfalfa (Medicago sativa) is the most widely cultivated and important forage crop worldwide, owing to its high protein content. However, alfalfa Fusarium root rot seriously affects and restricts the yield and quality. This study explores the response mechanism of alfalfa to Fusarium root rot. we used transcriptomic and proteomic methods to analyze differentially expressed genes (DEGs) and differentially expressed proteins (DEPs) in alfalfa inoculated with Fusarium acuminatum on 0, 3, and 13 days. In total, 13,017 DEGs (6902 upregulated, 6115 downregulated) and 4830 DEPs (697 upregulated, 659 downregulated) were identified. Gene Ontology (GO) and Kyoto and Encyclopedia of Genes and Genomes (KEGG) analyses indicated that the DEGs and DEPs were mainly enriched in t

SUBMITTER: Shi Z 

PROVIDER: S-EPMC12351649 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature