Effects of meeting exercise guidelines on depression and anxiety in multiple sclerosis - a systematic review and meta-analysis.

ABSTRACT:

Background

Depression and anxiety are common in multiple sclerosis (MS), significantly affecting quality of life. Previous studies on exercise interventions for mental health in persons with MS (PwMS) have shown mixed results, partly due to inconsistent adherence to the Physical Activity Guidelines for Multiple Sclerosis (PAG-MS).

Objective

This study aimed to evaluate the effects of PAG-MS-compliant exercise on depression and anxiety outcomes in PwMS.

Methods

A systematic search was performed in EMBASE, PsycINFO, Web of Science, SPORTDiscuss, PubMed, Scopus, and CINAHL through October 2024 to identify randomized controlled trials (RCTs). Eligible studies involved adults with MS and focused on exercise regimens compliant with PAG-MS. Comparisons were made with non-PAG

SUBMITTER: Fakorede S 

PROVIDER: S-EPMC12352009 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature