Research protocol design and implementation of a hybrid no-touch and low-touch prospective observational study during the COVID-19 public health emergency: the VISION study.

ABSTRACT:

Abstract

Introduction

The conduct of clinical research is essential during public health emergencies, including COVID-19, to characterise the natural history of the infection to inform case definitions, identify risk factors for severe disease, transmission patterns, short and long-term complications and safe and effective treatments and vaccines. Policies aimed at mitigating transmission of SARS-CoV-2 proved challenging to conduct clinical research. Here, we describe the Vital Status and Outcomes of COVID-19 (VISION) study, a hybrid no-touch and low-touch clinical research protocol following participants recently infected with SARS-CoV-2.

Methods and analysis

In this prospective longitudinal no-touch and low-touch observational study of recent SARS-CoV-2 infection,

SUBMITTER: Straub B 

PROVIDER: S-EPMC12352250 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature