Trionic All-optical Biological Voltage Sensing via Quantum Statistics.

ABSTRACT: Quantum confinement in monolayer semiconductors results in optical properties intricately linked to electrons, which can be manipulated by external electric fields. These optoelectronic features offer untapped potential for studying biological electrical activity. In addition to their relatively high quantum yields, picosecond level emission lifetimes make these materials particularly promising for monitoring biological voltages with high spatiotemporal resolution. To this end, we investigate exciton to trion conversion in angstrom thick semiconductors to experimentally demonstrate label-free, dual-polarity, all-optical detection of electrical activity, via changes in photoluminescence, in cardiomyocyte cultures with ultrahigh temporal resolution. We devise a physical model to elucidate th

SUBMITTER: Ren Y 

PROVIDER: S-EPMC12352334 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature