Cognitive behavioral therapy for antiretroviral therapy adherence and treatment outcomes among people living with HIV: a systematic review and meta-analysis.

ABSTRACT: Cognitive behavioral therapy has emerged as a promising intervention to enhance antiretroviral therapy adherence among people living with HIV. Here we conducted a systematic review and meta-analysis to evaluate the efficacy of cognitive behavioral therapy to improve antiretroviral therapy adherence, HIV viral load, viral suppression and CD4 counts. A total of 20 randomized controlled trials involving 1,739 people living with HIV were included, with most of the studies categorized as having low risk of bias. We show that cognitive behavioral therapy was associated with improved antiretroviral therapy adherence, with more pronounced effects for people living with HIV with psychiatric comorbidities and in studies conducted in low- and middle-income countries. No statistically significant find

SUBMITTER: Coelho DRA 

PROVIDER: S-EPMC12352344 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature