Homological landscape of human brain functional sub-circuits.

ABSTRACT: Human whole-brain functional connectivity networks have been shown to exhibit both local/quasilocal (e.g., set of functional sub-circuits induced by node or edge attributes) and non-local (e.g., higher-order functional coordination patterns) properties. Nonetheless, the non-local properties of topological strata induced by local/quasilocal functional sub-circuits have yet to be addressed. To that end, we proposed a homological formalism that enables the quantification of higher-order characteristics of human brain functional sub-circuits. Our results indicated that each homological order uniquely unravels diverse, complementary properties of human brain functional sub-circuits. Noticeably, the H1 homological distance between rest and motor task was observed at both whole-brain and sub-circ

SUBMITTER: Duong-Tran D 

PROVIDER: S-EPMC12352577 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature