The father's singing voice may impact premature infants' brain more than their mother's: A NICU single-arm exploratory study protocol and preliminary data on a singing and EEG framework based on the fundamental frequency of voice and kinship.

ABSTRACT: This article reports the protocol of a single-arm exploratory study investigating the impact of singing on the brain activity of premature infants in the Neonatal Intensive Care Unit (NICU). The study focuses on how the differentiation of voices, as defined by the fundamental frequency (F0) shaped by biological sex and kinship, influences neurophysiological responses when measured by electroencephalography (EEG). Premature infants, who are highly sensitive to auditory stimuli, may benefit from music-based interventions; however, there is limited understanding of how voice variations between male and female caregivers, and whether they are biologically related, affect brain activity. Our protocol outlines a structured intervention where infants are exposed to singing by four facilitators -

SUBMITTER: Papatzikis E 

PROVIDER: S-EPMC12352647 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature