High seroprevalence of antibodies to Dengue, Chikungunya, and Zika viruses in Dire Dawa, Ethiopia: A cross-sectional survey in 2024.

ABSTRACT:

Background

Aedes-borne diseases infect millions of people each year. In the last decade several arbovirus outbreaks have been reported in Ethiopia. Arbovirus diagnosis and surveillance is lacking, and the true burden is unknown.

Methods

In this study we conducted a seroprevalence survey using a commercially available test kit that tests for immunological responses to IgM and IgG for dengue (DENV), Zika (ZIKV), and chikungunya (CHIKV) viruses in Dire Dawa city, eastern Ethiopia. A total of 339 individuals were sampled using a household-based clustered design. As a contextual comparison, a secondary survey was conducted among 180 individuals in Addis Ababa, where no Aedes-borne virus outbreaks have been reported.

Findings

We found a high IgG seroprevalence for DENV (76%

SUBMITTER: Parker DM 

PROVIDER: S-EPMC12352872 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature