Emergence and Dynamics of Delusions and Hallucinations Across Stages in Early Psychosis.

ABSTRACT:

Background

Hallucinations and delusions are often grouped together as positive symptoms of psychosis. However, recent evidence suggests that they may be driven by distinct computational and neural mechanisms. Examining the time course of their emergence may provide insights into the relationship between these underlying mechanisms.

Methods

Participants from the second (N = 719) and third (N = 699) iterations of the North American Prodrome Longitudinal Study (NAPLS 2 and 3) were assessed for timing of clinical high risk for psychosis (CHR-P)-level delusion and hallucination onset. Pre-onset symptom patterns in patients with first-episode psychosis from the Prevention and Early Intervention Program for Psychosis (PEPP-Montréal) (N = 694) were also assessed. Symptom onset was d

SUBMITTER: Mourgues-Codern C 

PROVIDER: S-EPMC12353309 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature