RNAproDB: A Webserver and Interactive Database for Analyzing Protein-RNA Interactions.

ABSTRACT: We present RNAproDB (https://rnaprodb.usc.edu/), a new webserver, analysis pipeline, database, and highly interactive visualization tool, designed for protein-RNA complexes, and applicable to all forms of nucleic acid containing structures. RNAproDB computes several mapping schemes to place nucleic acid components and present protein-RNA interactions appropriately. Various structural annotations are computed including non-canonical base-pairing geometries, hydrogen bonds, and protein-RNA and RNA-RNA water-mediated interactions. This information is presented through integrated visualization and data tools. Subgraph selection facilitates studying smaller components of the interface. Molecular surface electrostatic potential can be visualized. RNAproDB enables analyzing and exploring experime

SUBMITTER: Mitra R 

PROVIDER: S-EPMC12353319 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature