Inhalational exposures associated with risk of interstitial lung disease: a systematic review and meta-analysis.

ABSTRACT:

Rationale

Inhalational exposures are associated with risk of developing interstitial lung disease (ILD), yet the relationship between specific exposures and ILD is poorly characterised.

Objective

Identify inhalational exposures associated with ILD and estimate the effects of exposures on ILD risk.

Methods

MEDLINE and EMBASE databases were searched from 1990 to 2022 to identify inhalational exposures associated with ILD diagnosis. ILDs where causality is well-established (hypersensitivity pneumonitis, pneumoconiosis) and sarcoidosis were excluded. Two independent reviewers screened abstracts with full-text review and data extraction of eligible studies. Where possible, data were pooled and multilevel meta-analysis was specified using a random effects model. Sources of

SUBMITTER: Lee CT 

PROVIDER: S-EPMC12354187 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature