ECG-based beat-to-beat assessment of AV node conduction properties during AF.

ABSTRACT:

Introduction

The refractory period and conduction delay of the atrioventricular (AV) node play a crucial role in regulating the heart rate during atrial fibrillation (AF). Beat-to-beat variations in these properties are known to be induced by the autonomic nervous system (ANS) but have previously not been assessable during AF. Assessing these could provide novel information for improved diagnosis, prognosis, and treatment on an individual basis.

Methods

To estimate AV nodal conduction properties with beat-to-beat resolution, we propose a methodology comprising a network model of the AV node, a particle filter, and a smoothing algorithm. The methodology was evaluated using simulated data and using synchronized electrogram (EGM) and ECG recordings from five patients in the int

SUBMITTER: Karlsson M 

PROVIDER: S-EPMC12354475 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature