Post-mortem forensic application of proteomics on human ribs: Investigating the phenomenon of vital reaction.

ABSTRACT: The research upon vital reactions is a hot topic in forensic pathology. However, there are very few studies which focus on the bone tissue and scientific data are currently limited to conventional histopathology. The skin and the muscle are also faster than the bone in the healing process. Therefore, the possibility to establish the timing of skeletal traumatic injury is difficult especially for short survival times (peri-mortem interval). For these reasons, bone marrow may represent a dynamic and potentially useful substrate for the identification of bone lesion vitality. Furthermore, novel omics techniques such as the untargeted proteomics could really improve the investigation of reliable forensic markers. This study provides the application of proteomics on human bone marrow of traumat

SUBMITTER: Galante N 

PROVIDER: S-EPMC12354616 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature