Engineered Whey Protein Nanoparticles for Intracellular Drug Delivery.

ABSTRACT: Protein-based nanoparticles, composed of water-soluble proteins, represent a promising platform for reducing side effects during drug delivery. They enhance the solubility, stability, and bioavailability of hydrophobic therapeutic agents while maintaining high biocompatibility and biodegradability in vivo. These nanoparticles are nontoxic and capable of encapsulating both hydrophilic and hydrophobic drugs, making them highly versatile. In this study, we explored the potential of whey proteins derived from bovine milk to engineer nanoparticles for efficient drug delivery. Whey proteins, traditionally regarded as waste byproducts of cheese production, have recently gained attention for their potential in drug encapsulation, thanks to their excellent biocompatibility and biodegradability. We

SUBMITTER: Torresan V 

PROVIDER: S-EPMC12355329 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature