Quality of antidiabetic medicines in 13 sub-Saharan African countries: a cross-sectional survey.

ABSTRACT:

Background

The burden of diabetes is rising dramatically in low- and middle-income countries. The menace of substandard and falsified drugs constitutes a major hazard that compromises healthcare. The DIABDAF study aimed to assess the quality of routinely used antidiabetic drugs including oral drugs and insulins in sub-Saharan Africa.

Methods

Drugs were collected in 13 sub-Saharan African cities in licensed and unlicensed places of sales between February 2020 and March 2023. Chemical analyses were conducted blindly in a public laboratory following recommended good laboratory practices. Drug quality was classified based on the ratio of measured to expected active ingredient dosage: 95-105% as good (A), 85-94·99% or 105·01-115% as low (B), and below 85% or above 115% as very lo

SUBMITTER: Antignac M 

PROVIDER: S-EPMC12355408 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature