Epidemiological and clinical characteristics of patients in the alveolar echinococcosis registry, France, 1982 to 2021.

ABSTRACT: BACKGROUNDEchinococcus multilocularis is a parasite causing alveolar echinococcosis (AE), a severe disease affecting primarily the liver. Surveillance of this non-notifiable disease in France is performed by the National Reference Center for Echinococcoses (NRC-E).AIMWe aimed to analyse changes in epidemiological, clinical and survival data of patients with AE over time.METHODSWe described and analysed data from 906 AE patients reported to the NRC-E over three periods: 1982-1999, 2000-2010 and 2011-2021, using regression methods and survival analysis methods.RESULTSAt diagnosis, the median age of the patients was 60.0 years, most (770; 85.0%) resided in an endemic region and 483 (53.3%) in a rural area. The percentage of asymptomatic patients increased significantly from 19.1% (48/2

SUBMITTER: Knapp J 

PROVIDER: S-EPMC12355909 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature