RpNGS: an automated platform for pathogen identification and monitoring in clinical metagenomics data.

ABSTRACT:

Background

The capacity of metagenomic sequencing-based diagnostics to fully identify infections have made them useful instruments in clinical practice. We introduce an interactive platform that runs on a local server-class hardware resource and implements a number of open-source programs.

Results

RpNGS integrates an interactive tabular interface for the management of experimental processes, patient metadata, and automated sequencing analysis. This technology optimizes clinical reporting by autonomously generating standardized reports in Word format. We have utilized the platform on an artificial microbial community reference panel and several clinical metagenomics datasets from public databases to demonstrate the efficacy of this workflow.

Conclusions

RpNGS is an inn

SUBMITTER: Zhou J 

PROVIDER: S-EPMC12356182 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature