Dating Discrepancies on Research Ultrasonography and Risk of Pregnancy Loss in a Prospective Cohort.

ABSTRACT:

Objective

To estimate the risk associated with discrepancies between last menstrual period (LMP)-based and ultrasound-based gestational dating and pregnancy loss in a prospective cohort of individuals of normal fertility who underwent standardized early-pregnancy ultrasonography.

Methods

Participants in a community-based, prospective pregnancy cohort were recruited preconceptionally or in early pregnancy. Participants underwent standardized research ultrasonography targeted for the sixth week of gestation. We calculated the magnitude of lag between ultrasound-based age and LMP-based age at the research ultrasonogram. Cox proportional-hazards models were used to estimate the association between this difference and pregnancy loss. To assess for effect modification, analyses we

SUBMITTER: Sundermann AC 

PROVIDER: S-EPMC12356491 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature