Global research landscape of retinoblastoma biomarkers: a multidisciplinary bibliometric analysis based on multiple databases (2005-2025).

ABSTRACT:

Objective

Research exploring biomarkers for retinoblastoma (RB) diagnosis exists; however, their specific impact on RB has not been thoroughly investigated through systematic quantitative analysis. This study aims to analyze the research landscape and hotspots of RB biomarkers from 2005 to 2025, providing a theoretical reference for future investigations.

Methods

We retrieved publications from the Web of Science and Scopus databases published between 2005 and 2025, followed by analysis using R software, VOSviewer, and CiteSpace tools.

Results

From 2005 to 2025, annual publication output exhibited a steady upward trajectory, with notably accelerated growth observed between 2013 and 2021, followed by a moderated pace from 2021 to 2024. China led in publication volume, f

SUBMITTER: Peng Z 

PROVIDER: S-EPMC12356788 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature