Effects of the cardiac cycle on carotid intima-media thickness in ELSA-Brasil baseline assessment.

ABSTRACT:

Background

It is unclear to what extent the cardiac cycle influences carotid intima-media thickness CIMT values, especially in individuals with major Cardiovascular Risk Factors (CVRF). The authors analyzed CIMT variability across the cardiac cycle using baseline data from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

Methods

The authors analyzed data from 9546 ELSA-Brasil participants, aged 35 to 74 in six Brazilian cities. CIMT image acquisition was ECG-gated during three cardiac cycles (70 to 90 frames). The authors calculated the Coefficient of Variation (CV), range, and interquartile range to assess variability using frame-by-frame data. In addition, the authors stratified the sample according to the presence of five major CVRFs: hypertension, diabetes

SUBMITTER: Silva YCG 

PROVIDER: S-EPMC12357139 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature