The clinical characteristics and inflammatory endotypes of chronic rhinosinusitis with nasal polyps in Southern China: A multi-center, cross sectional study.

ABSTRACT:

Background

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a prevalent inflammatory disease characterized by prolonged symptoms and frequent recurrences. According to clinical and pathological characteristics, patients can be classified into different endotypes. Limited data exist on the endotype distribution of CRSwNP in Southern China.

Objective

This study aimed to delineate the clinical characteristics and inflammatory endotypes of CRSwNP in Southern China, with a focus on the impact of asthma and allergic comorbidities on disease severity and recurrence.

Methods

This multi-center, cross-sectional study analyzed 375 adult patients with CRSwNP from 3 hospitals in Southern China. Patients were classified into type 2 and non-type 2 endotypes based on clinical cri

SUBMITTER: Xu Z 

PROVIDER: S-EPMC12357244 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature