Association between basal metabolic rate and cognitive function in Chinese older adults: the mediating effect of sarcopenia.

ABSTRACT:

Background

Cognitive aging poses a major worldwide health concern. The association between basal metabolic rate (BMR) and cognition isn't well understood. This research examines sarcopenia's potential role as a mediator: linking BMR to cognitive function.

Methods

Analysis used China Health and Retirement Longitudinal Study (CHARLS) data from adults aged ≥ 60 years (2015, 2018 waves). Mental integrity and episodic memory recall assessed cognitive function. Linear multivariate analyses were conducted to examine the associations between BMR, sarcopenia, and cognitive function, adjusting for potential confounders. Mediation analyses explored sarcopenia's role in the BMR-cognitive function relationship. Restricted cubic splines assessed nonlinear relationships, and subgroup analy

SUBMITTER: Ding H 

PROVIDER: S-EPMC12357453 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature