Hidden transmissions of Pseudomonas aeruginosa ST111 -the importance of continuous molecular surveillance.

ABSTRACT:

Background

A series of transmission of Pseudomonas aeruginosa ST111 bla_VIM-2, previously undetected by standard surveillance, was discovered in a tertiary care hospital in Northern Germany through molecular genetic monitoring. Hence, environmental sampling was initiated to find the source of infection.

Methods

First, routine epidemiological data ruled out patient-to-patient transmission and two initial diagnoses were assessed as externally acquired. After the discovery of the highly related cluster by whole genome sequencing, a more detailed epidemiological analysis was carried out, including previous hospitalizations. An environmental investigation was initiated due to a possible connection of transmissions with an intensive care unit.

Results

Between 2018

SUBMITTER: Jasuja JK 

PROVIDER: S-EPMC12357456 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature