Efficacy and safety of CT-guided microwave ablation for stage I non-small cell lung cancer in elderly patients.

ABSTRACT:

Objective

To evaluate the efficacy of MWA for patients aged ≥ 75 years with stage I NSCLC, and to explore the impacts of age and comorbidities on the long-term outcomes.

Methods

Patients with stage I NSCLC underwent MWA between November 2016 and December 2020 were retrospectively enrolled. Patients were stratified into two cohorts: ≥ 75 years and < 75 years. Propensity score matching was implemented to control selection bias. Primary endpoints included overall survival (OS), cancer-specific survival (CSS), and recurrence-free survival (RFS). Secondary endpoints included independent risk factors influencing OS.

Results

138 patients were successfully matched, with 69 in each group. The 1-, 3-, and 5-year OS were 95.7%, 82.6%, and 72.8% in patients aged ≥ 75 years, while

SUBMITTER: Peng J 

PROVIDER: S-EPMC12357467 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature