Improved clinical outcomes with a modified warming protocol in donor oocyte cycles.

ABSTRACT:

Background

Recent studies have attempted to improve laboratory efficiency while preserving clinical outcomes by shortening the time to warm cryopreserved embryos, though it is still unclear for oocytes. This study thus aimed to evaluate the effects of a modified warming protocol (MWP) on embryonic development and pregnancy outcomes of vitrified donor oocytes.

Methods

The data of this retrospective cohort study were collected from women who underwent donor cycles (fresh or vitrified oocytes) at Lee Women's Hospital, Taiwan, from January 2019 to August 2024. The sample included 13,103 donor oocytes, divided into three groups: conventional warming protocol (CWP) group (n = 8506), MWP group (n = 980), and fresh group (n = 3617).

Results

Survival rates after oocyte warming

SUBMITTER: Lee CI 

PROVIDER: S-EPMC12357474 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature