AutoMethyc: an automated methylation analysis for massively parallel sequencing data.

ABSTRACT:

Motivation

Bisulfite sequencing (BS-Seq) enables a comprehensive and detailed analysis of DNA methylation patterns at single-nucleotide resolution. While methylation differences can contribute to various diseases, their sincronous occurrence at distinct loci complicates understanding. Therefore, advanced tools are essential to facilitate the identification and analysis of methylation programs and patterns.

Results

AutoMethyc provides a comparative approach by integrating different algorithms coordinated and optimized for use on desktop computers and servers. The workflow evaluates the methylation status from different perspectives, facilitating interpretation in an interactive HTML report, incorporating new co-methylation analyses for marker identification, as well as explor

SUBMITTER: Ambriz-Barrera F 

PROVIDER: S-EPMC12357496 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature