Sampling strategies for digestive system flora studies: current research and perspectives.

ABSTRACT:

Background

The digestive system is significantly associated with the incidence and progression of various diseases. Investigating its microbial community will aid in the diagnosis, treatment, and prognostication of digestive pathologies. Microbial composition varies not only between distinct organs but also within different regions of the same organ. Additionally, dynamic shifts in microbial composition occur throughout various phases of the disease, complicating research. This study systematically evaluated the biological samples and diverse collection methods employed in digestive system microbiota research, with the aim of guiding sample selection and collection strategies for future microbial studies.

Methodology

We conducted a comprehensive literature review using profe

SUBMITTER: Liu X 

PROVIDER: S-EPMC12357548 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature