Intravoxel incoherent motion imaging and dynamic susceptibility contrast perfusion MRI in differentiation between recurrent intracranial tumor and treatment-induced changes.

ABSTRACT:

Purpose

To compare intravoxel incoherent motion (IVIM) imaging to dynamic susceptibility-weighted contrast (DSC) perfusion MRI in differentiating tumor recurrence from treatment-induced changes.

Methods

Our prospective study included patients previously treated with radiotherapy for intracranial tumors who later developed a new or increasing contrast-enhancing lesion. The final diagnosis was based on neuropathology or 6-month follow-up. MR examinations were performed for calculation of the perfusion fraction (f) using the IVIM technique and relative blood volume (rCBV) using DSC perfusion. Measurements of f and rCBV were made by two independent readers in hotspots when possible, but otherwise in the whole enhancing region. Measures of rCBV were normalized to the contralatera

SUBMITTER: Hellstrom J 

PROVIDER: S-EPMC12357801 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature