Analysis of the impact of nodular calcification on clinical outcome after drug-coated balloon angioplasty for femoropopliteal lesions.

ABSTRACT:

Purpose

This study aimed to reveal the impact of nodular calcification (NC) on restenosis risk in patients undergoing femoropopliteal drug-coated balloon (DCB) angioplasty for symptomatic atherosclerotic peripheral artery disease.

Methods

We retrospectively analyzed 568 patients who underwent endovascular therapy with DCB for de novo femoropopliteal lesions under intravascular ultrasound guidance between November 2017 and February 2021 at seven cardiovascular centers in Japan. Patients with lesions without calcification were excluded from the study. The patients were classified into two groups based on the presence or absence of NC: the NC [ +] group (n = 200) and the NC [-] group (n = 368). The main outcome was the primary patency at 3 years. Cox proportional hazards analys

SUBMITTER: Mori S 

PROVIDER: S-EPMC12357817 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature